Junior Post-Doctoral Researcher in Human Organoid Engineering and Disease Modeling

institute for bioengineering of catalonia (ibec) • Spain

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AI Summary

Seeking a Junior Post-Doctoral Researcher (within 3 years of PhD defense) to advance human organoid platforms using hPSC for disease modeling and drug screening. Focus on bioengineering approaches, scalable organoid differentiation, and quantitative analysis. Mentorship and project management included.

Key Highlights

Post-doctoral position in bioengineering and regenerative medicine with organoid platforms

Focus on biomimetic hydrogels, organ-on-chip, and 3D bioprinting for organoid development

Mentorship of PhD/Master’s students and project management under tight deadlines

Key Responsibilities

Develop and apply bioengineering approaches to enhance organoid differentiation and reproducibility, including biomimetic hydrogel synthesis and 3D bioprinting

Establish scalable human organoid differentiation protocols from hPSCs in 2D and 3D cell culture systems

Design and implement quantitative/qualitative assays to monitor molecular, metabolic, and functional changes during organoid development

Define standardized operational procedures (SOPs) for research workflows

Analyze complex datasets, author high-impact publications, and present findings at international conferences

Supervise and mentor PhD/Master’s students, manage project milestones, and prepare technical reports

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Technical Skills Required

Human pluripotent stem cell (hPSC) culture and differentiation Bioengineering technologies (microfabrication, biomaterials, organ-on-chip, bioprinting) Quantitative and qualitative image analysis (confocal microscopy, live imaging)

Benefits & Perks

Full-time open-ended contract

23 working days of paid holidays

Flexible working hours and work-life balance measures

Training and professional development opportunities

Support for visa/work permit and relocation assistance for foreigners

Stimulating interdisciplinary research environment

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Nice to Have

Quantitative imaging in 2D/3D organoid and live imaging setups

Custom image processing scripts for quantification

CRISPR/Cas9 genome editing experience

Bulk and single-cell RNA sequencing data analysis

Job Description

Introduction to the vacant position:

The Pluripotency for organ regeneration Group at the Institute for Bioengineering of Catalonia (IBEC) is looking for a Junior Post-doctoral Researcher up to 3 years after PhD thesis defense, to conduct her/his postdoctoral training on the development of advanced human organoid platforms based on hPSC for disease modelling and drug screening applications.

Main tasks and responsibilities:

• Application of engineering approaches to define controlled cell-to-cell and cell-to-ECM microenvironments to enhance organoid differentiation and reproducibility, including synthesis of biomimetic hydrogels, development of organ-on-chip approaches and 3D bioprinting.

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