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Director, Digital Governance

Sarah Cannon Research Institute • Knoxville Metropolitan Area
Full Remote
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Lead IT governance for data, AI, and agent systems in a GxP clinical-research environment. Design and operate lifecycle controls for AI and autonomous agents powering the Agent Factory. Establish data governance frameworks ensuring quality, integrity, and compliance across clinical and operational systems.

Key Highlights
Accountable owner for IT governance including data, AI, and agent governance in GxP clinical-research environment
Design and operate lifecycle controls for AI and autonomous agents aligned with Enterprise standards
Establish data governance framework with policies, standards, and controls for data quality and integrity
Key Responsibilities
Operate IT SOPs as inspection-defensible controls through ownership, SOP-to-control traceability, change-impact governance, and effectiveness monitoring
Author, maintain, and operationalize IT SOPs and controlled documents to GxP, 21 CFR Part 11/Annex 11, and ALCOA+ expectations
Design, build, and operate SCRI's AI and agent governance framework aligned with Enterprise controls
Define and operationalize lifecycle governance for AI and agentic systems including intended-use definition, model and agent documentation, validation, monitoring, and retirement/archival
Establish governance requirements including clinical-expertise review for GxP AI, participant-disclosure handling for AI used in clinical trials, and model-archival protocols
Own SCRI's data governance framework including policies, standards, and controls for data quality, integrity, lineage, and compliance
Establish metadata, lineage, classification, and data-quality standards with access and lifecycle controls embedded in platforms
Serve as escalation point for data-integrity risks affecting clinical, operational, or regulatory outcomes
Define, build, and operate KPI-driven governance dashboards providing continuous evidence-based view of control health, risk, and remediation
Identify gaps and drive corrective actions to closure, reporting governance posture to executive leadership
Communicate complex governance and risk topics clearly to executive leadership, regulators, and non-technical stakeholders
Operate effectively in matrixed organizations influencing outcomes without direct authority
Partner with Quality during inspection responses, findings remediation, and CAPAs related to data integrity
Technical Skills Required
IT governance Data governance AI governance GxP/GCP regulatory frameworks
Benefits & Perks
Remote work
Comprehensive benefits package

Job Description

Our people are the foundation of our success. By joining our growing team at Sarah Cannon Research Institute (SCRI), a subsidiary of McKesson, you will have the opportunity to become part of one of the largest community-based cancer programs to advance oncology treatments and improve outcomes for cancer patients across the globe. We look for mission-driven candidates who have a desire to advance the fight against cancer and make a difference in the lives of patients diagnosed with cancer every day.
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